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A month after every adult in the U.S. became eligible for the vaccine, a distinct geographic pattern has emerged: The highest vaccination rates are concentrated in the Northeast, while the lowest ones are mostly in the South.

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More than a dozen states quickly embraced new federal guidelines that say fully vaccinated Americans no longer need to wear masks indoors or out in most cases. But other states and cities and some major businesses hesitated amid doubts about whether the approach is safe or even workable.