A Berkeley County man shot his wife and her two teenage nieces Wednesday afternoon because he couldn't handle being separated from her, according to neighbors who knew the couple.

Darryl Edward Flowers, 35, is accused of showing up at the house at 52 Elmwood Place around 4 p.m. Wednesday and fatally shooting his estranged wife and wounding the two girls, who were taken to a hospital.

He was last seen Wednesday night driving a stolen teal 1997 Ford Explorer toward Interstate 26, according to Sheriff's Maj. Rick Ollic.

The neighborhood is a street of single-story brick houses off U.S. Highway 52 just north of Goose Creek.

The woman's body was found outside the front door of her house, Coroner Bill Salisbury said. He did not identify her Wednesday, but several neighbors called her Tammy.

As investigators worked the scene behind the yellow crime tape, a woman got out of her car and ran toward the house crying out over and over, "Tammy, oh, no, Tammy! I tried to warn you! Oh, Tammy!"

Several neighbors said the weeping woman was a co-worker of the woman who was killed. Deputies took her aside.

Rhea Williams lives a few houses up the street from the crime scene. She said the woman and Flowers were separated but he kept coming back to watch the house.

"Just my instincts told me something was a little off with him, but I never saw this coming," Williams said.

She said the girls were the woman's teenage nieces. There was no word Wednesday on their condition.

Several other neighbors who did not want to be named confirmed her story.

Flowers drove off in a blue Chevrolet Impala, then abandoned it on Amy Drive in Goose Creek, Ollic said. Flowers then got a ride to Lincolnville and stole the Explorer around 7:30 p.m., Ollic said.

Flowers has ties to New York, although nobody could say where he was going.

The stolen Explorer has the S.C. license JPY 963. Anybody who sees Flowers or the SUV is asked to call a law-enforcement agency. Flowers is considered armed and dangerous and should not be approached, Ollic said.

Reach Dave Munday at 937-5553.