Dr. H. Hugh Fudenberg, an immunologist and former professor and chairman of the department of basic and clinical immunology and microbiology with the Medical University of South Carolina, died March 15. He was 85.

Fudenberg, a son of Eastern European immigrants, was a pioneer in the field of immunology and immunotherapy. He was internationally referred to as the founder of clinical immunology.

His research included experimental treatments for Alzheimer's and Lou Gehrig's diseases, chronic fatigue-immune dysfunction syndrome and autism. His treatment involved the extraction of healthy blood cells, typically from a patient's relative, that were then injected into the patient. His early work involved the isolation of a protective blood substance used in the treatment of bone cancer.

In 1980, Fudenberg was named the recipient of the Carl Neuberg Medal for his biomedical work. He also was awarded an honorary doctorate in medical sciences from the University of Kuopio in Finland. Scientists in Bejing, China gave him a golden key to the city and awarded to him two honorary professorships.

He was the editor of the International Journal of Clinical Immunology and Immunopathology and the author of the textbook "Basic and Clinical Immunology."

He is survived by four sons: Drew Fudenberg, Brooks R. Fudenberg, David M. Fudenberg and Hugh H. Fudenberg.

There will be a celebration of life at 6 p.m. today at The Lodge at Lake Bowen Commons, 7116 Highway 9, Inman, S.C.

In lieu of flowers, donations can be made to any charity that supports biomedical research.