A teenage girl and middle-aged man were killed and a teenager was injured after a pickup truck lost control and struck a tree in rural Colleton County Saturday.

The wreck was reported about 12:20 p.m. on Oregon Trail Road, near White Hall Road, in the southern end of the county, Colleton County Fire and Rescue Director Barry McRoy said.

Oregon Trail is a lightly traveled dirt road that goes through a swamp and a large tree farm. No houses are within a mile of the accident site, McRoy said.

McRoy said a full-size 1999 Ford-F250 ran off the road and struck a tree at high speed, splitting the truck in two.

The driver and passenger in the cab died at the scene. A 13-year-old riding in the bed of the truck was thrown from the wreck and escaped with minor injuries, McRoy said.

The female driver, 17, of Green Pond, was wearing a seat belt, but the male passenger, 40, of Walterboro, was not, according to the South Carolina Highway Patrol.

The victims were trapped in the mangled pickup and had to be extricated with special equipment by rescue workers after a wrecker pulled it from the tree, McRoy said.

The Colleton County coroner’s office has not released the victims’ names.

The Highway Patrol is investigating the crash.